Is Molybdenum Deficiency the Cause?
نویسندگان
چکیده
Sulfur dioxide and other so-called sulfiting agents as additives in foods and drugs may cause severe allergic reactions in susceptible individuals, especially asthmatics. The most widely used chemical preservatives, they have become a subject of increasing concern since 1976. The issue was recently brought to national attention by a CBS "60 Minutes" report on sulfite sensitivity aired twice in 1983. "Sulfites" is a generic term for a group of compounds including sulfur dioxide, sodium sulfite, sodium and potassium bisulfite and sodium and potassium metabisulfite. They are antioxidants useful for their antimicrobial action and prevention of enzymatic and nonenzymatic discoloration (browning) of foods. Sulfites have been listed by the FDA as Generally Recognized as Safe (GRAS) for use in food, with a proviso, however, that they not be used in foods which are substantial sources of thiamine (vitamin Bl). Sulfites destroy thiamine. Currently, the Center for Science in the Public Interest, armed with data from Scripps Clinic and Research Foundation and other institutions, is applying pressure on the FDA to tighten restrictions. Sulfite-Containing Foods There is a history of use dating back to ancient Egypt and Rome when fumes of burning sulfur were used as a sanitizing agent in winemaking. The use of sulfur dioxide persists in several stages of wine-making today. Virtually all domestic and foreign wines and beers and many soft drinks contain the preservative. Sulfiting of other foods, particularly meats and fish, is centuries old but the popularity of salad bars in restaurants has probably brought consumption to an all-time high. Fruits and vegetables dipped in bisulfite look fresh and crisp and won't discolor even as they become stale. Restaurants also use them on shellfish and fried potatoes. Sulfur dioxide is used on virtually all dehydrated fruits and vegetables (eg. apricots, garlic powder) to preserve, color and flavor as well as to aid in the retention of ascorbic acid and carotene. Sulfites are commonly used in vinegar, pickles, relishes, olives and sauerkraut and in concentrates of bulk juices and purees such as tomato (eventually to be processed into consumer products). They are used in the processing of many food ingredients such as gelatin, beet sugar, corn sweeteners
منابع مشابه
Molybdenum Cofactor Biology and Disorders Related to Its Deficiency; A Review Study
Background: Molybden, as a vital and essential micronutrient is directly involved in the metabolism of other elements including carbon, sulfur, and nitrogen. Molybdenum alone is not biologically active unless it binds to specific cofactors. Except for the bacterial nitrogenase, which contains molybdenum-Iron complex, molybdenum cofactor (Moco) is considered as the bioactive component placed in ...
متن کاملبررسی اثر پالس بر خواص ساختاری و اپتیکی لایههای نازک اکسید مولیبدن در لایهنشانی به روش کندوپاش مغناطیسی پالس قدرت بالا (HiPIMS)
In this study, molybdenum oxide thin films are deposited by using high power impulse magnetic sputtering (HiPIMS) at different pulses length of 60, 90, 120, 150 and 180 μs on glass substrates in a combination of reactive and non-reactive gases with a ratio of O2/Ar = 0.66. The structural and optical properties of these coatings are studied. The chemical composition of these metal oxides is dete...
متن کاملExperimental Copper Deficiency, Chromium Deficiency and Additional Molybdenum Supplementation in Goats – Pathological Findings
Secondary copper (Cu) deficiency, chromium (Cr) deficiency and molybdenosis (Mo) has been suggested to cause the "mysterious" moose disease in the southwest of Sweden. The present experiment was performed on goats to investigate the clinical, chemical, and pathological alterations after 20 months feeding of a semi-synthetic diet deficient in Cu and Cr. Four groups were included in the study: co...
متن کاملبهینهسازی توپولوژی سازههای صفحهای به کمک روش SIMP و حذف مناطق شطرنجی
The SIMP approach is one of the most frequently used methods for topology optimization of structures. In this method, the relative density is expressed as a function of coordinates and varies from 0 to 1 within the design domain. Relative densities of 0 and 1 are associated to the existence and non-existence of the material, respectively. The finite element approach is usually utilized to analy...
متن کاملMolybdenum Cofactor and Sulfite Oxidase Deficiency
A universal molybdenum-containing cofactor is necessary for the activity of all eukaryotic molybdoenzymes. In humans four such enzymes are known: Sulfite oxidase, xanthine oxidoreductase, aldehyde oxidase and a mitochondrial amidoxime reducing component. Of these, sulfite oxidase is the most important and clinically relevant one. Mutations in the genes MOCS1, MOCS2 or GPHN all encoding cofactor...
متن کاملNew insights into the neuropathogenesis of molybdenum cofactor deficiency.
BACKGROUND Molybdenum cofactor deficiency (MOCOD) is a rare, progressive neurodegenerative disorder caused by sulphite oxidase enzyme deficiency. The neuropathological findings are consistent with a toxic insult to the brain that causes severe neuronal loss, reactive astrogliosis and spongiosis. The mechanisms responsible for these changes are unknown. METHODS The case is a male infant with M...
متن کامل